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Inhibitory Effect of Essential Oil from Fructus Alpiniae zerumbet on Endothelial-to-Mesenchymal Transformation Induced by TGF-β1 and down-regulating KLF4

2020-11-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Endothelial Mesenchymal Transformation (EndMT) contributes to the development of cardiovascular disease. Krüpple factor 4 (KLF4) is a zinc finger transcription factor whose N-terminus can recruit acetyltransferase to promote histone acetylation, thereby affecting the transcription activation of downstream genes. Our previous studies have shown that EOFAZ has pro...

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Literature Corpus work: 107d4007-f1a3-582a-8eb5-466381f6f6bb
DOI: 10.21203/rs.3.rs-107310/v1

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Inhibitory Effect of Essential Oil from Fructus Alpiniae zerumbet on Endothelial-to-Mesenchymal Transformation Induced by TGF-β1 and down-regulating KLF4DOI 10.21203/rs.3.rs-107310/v1Read

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