Article
Endothelial-to-mesenchymal transition: A novel therapeutic target for cardiovascular diseases.
Trends in cardiovascular medicine - 1 Aug 2017
Jackson Ampadu O, Zhang Jingjing, Jiang Zhisheng, Yin Kai
Abstract excerpt
Endothelial-to-mesenchymal transition (EndMT) is a complex biological process in which endothelial cells lose their specific markers and acquire a mesenchymal or myofibroblastic phenotype. Similar to epithelial-to-mesenchymal transition (EMT), EndMT can be induced by multiple stimulants such as cytokines and metabolic factors that play crucial roles in the development of the cardiovascular system. Recent studies...
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