Article

Iron deficiency induces maturation-dependent loss of pancreatic β-cells

2025-06-04

Abstract excerpt

<title>Abstract</title> <p>Pancreatic β-cells maintain glucose homeostasis by secreting insulin in response to rising blood glucose, a process fueled by mitochondrial ATP production. Iron, a core cofactor in the electron transport chain, is essential for this metabolic coupling. While the cytotoxic effects of iron overload are well known, the role of iron sufficiency during β-cell development remains unclear. Her...

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Literature Corpus work: 106ad105-aa4a-5f68-9299-b0579a1f9361
DOI: 10.21203/rs.3.rs-6626864/v1

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