Article

Excessive iron accumulation mediated oxidative stress and β-cell dysfunction via perturbations of insulin secretion in MIN6 cells

2020-01-01

Abstract excerpt

Type 2 diabetes mellitus (T2DM) is the predominant form of diabetes, with prevalence increasing steadily both in developed and developing countries. Defects in both insulin action and insulin secretion are known to contribute to the development of T2DM. Reactive oxygen species (ROS) mediated cellular oxidative damage has been implicated in cellular dysfunction in various organs and disease states. Exposure to high...

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Literature Corpus work: 43d31aeb-fb4a-53d0-8281-3f48cbee6c87
DOI: 10.34737/qzvvw

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