Article

tHapMix: simulating tumour samples through haplotype mixtures

2016-06-07

Abstract excerpt

<h4>Motivation</h4> Large-scale rearrangements and copy number changes combined with different modes of cloevolution create extensive somatic genome diversity, making it difficult to develop versatile and scalable oriant calling tools and create well-calibrated benchmarks. <h4>Results</h4> We developed a new simulation framework tHapMix that enables the creation of tumour samples with different ploidy, purity an...

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Literature Corpus work: 1067d552-000d-5d7e-a0b0-8e5256f578ac
DOI: 10.1101/057414

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