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Article

SVEngine: an efficient and versatile simulator of genome structural variations with features of cancer clonal evolution.

GigaScience - 1 Jul 2018

Xia Li Charlie, Ai Dongmei, Lee Hojoon, Andor Noemi, Li Chao, Zhang Nancy R, Ji Hanlee P

Abstract excerpt

Background: Simulating genome sequence data with variant features facilitates the development and benchmarking of structural variant analysis programs. However, there are only a few data simulators that provide structural variants in silico and even fewer that provide variants with different allelic fraction and haplotypes. Findings: We developed SVEngine, an open-source tool to address this need. SVEngine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29982625
DOI: 10.1093/gigascience/giy081
PMCID: PMC6057526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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