Article

The desmosomal cadherin Desmoglein-3 regulates YAP and phospho-YAP in keratinocyte responses to mechanical forces

2019-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Desmoglein 3 (Dsg3), plays a crucial role in cell-cell adhesion and tissue integrity. Increasing evidence suggests that Dsg3 acts as a regulator of cellular mechanotransduction, but little is known about its direct role in mechanical force transmission. The present study investigated the impact of cyclic strain and substrate stiffness on Dsg3 expression and its role in mechanotransduction. A dir...

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Literature Corpus work: 0fd2ad23-ac56-5caf-98d6-86821bacda6e
DOI: 10.1101/827725

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