Article

Integrative Proteomic Analysis Implicates Inhibition of Intracellular Protein Trafficking in Therapy-Induced Migrastasis in Prostate Cancer

2026-07-03

Abstract excerpt

<h4>Background</h4> Dysregulated cell migration leading to metastasis remains the primary cause of cancer-related mortality. It has been challenging to understand how cells regulate migration. We have previously created the first selective inhibitor of cell migration, KBU2046. Here, we use it as a probe to identify regulatory processes. <h4>Methods</h4> Metastatic and primary human prostate cancer cells were tre...

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Literature Corpus work: 0f9f5c1f-fc39-5e6e-a954-4c6bc6083883
DOI: 10.64898/2026.07.02.736165

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