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Intestinal cellular heterogeneity and disease development revealed by single-cell technology

1 Sept 2022

Abstract excerpt

The intestinal epithelium is responsible for food digestion and nutrient absorption and plays a critical role in hormone secretion, microorganism defense, and immune response. These functions depend on the integral single-layered intestinal epithelium, which shows diversified cell constitution and rapid self-renewal and presents powerful regeneration plasticity after injury. Derailment of homeostasis of the...

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PMID: 36045190
DOI: 10.1186/s13619-022-00127-6

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