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Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2022

Bhale Aishwarya Sudam, Venkataraman Krishnan

Abstract excerpt

Apolipoprotein A1 (ApoA1) is a member of the Apolipoprotein family of proteins. It's a vital protein that helps in the production of high-density lipoprotein (HDL) particles, which are crucial for reverse cholesterol transport (RCT). It also has anti-inflammatory, anti-atherogenic, anti-apoptotic, and anti-thrombotic properties. These functions interact to give HDL particles their cardioprotective...

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Identifiers

PMID: 36063649
DOI: 10.1016/j.biopha.2022.113634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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