Article
Apolipoprotein A5: Extracellular and Intracellular Roles in Triglyceride Metabolism.
Current drug targets - 1 Jan 2015
Forte Trudy M, Ryan Robert O
Abstract excerpt
This review addresses two major functions of apolipoprotein (apo) A5 including (1) its role in maintaining normal plasma levels of circulating triglyceride (TG) and (2) its role as a component of hepatic lipid droplets. ApoA5 is synthesized solely in the liver and circulating concentrations are extremely low. In the plasma, ApoA5 associates with TG-rich lipoproteins and enhances TG hydrolysis and remnant...
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