Article

Obesity-Associated Changes in Immune Cell Dynamics During Alphavirus Infection Revealed by Single Cell Transcriptomic Analysis

2024-10-13

Abstract excerpt

<h4>Summary</h4> Obesity induces diverse changes in host immunity, resulting in worse disease outcomes following infection with various pathogens, including arthritogenic alphaviruses. However, the impact of obesity on the functional landscape of immune cells during arthritogenic alphavirus infection remains unexplored. Here, we used single-cell RNA sequencing (scRNA-seq) to dissect the blood and tissue immune re...

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Literature Corpus work: 0f70ef9d-8710-570a-a42a-d3a33c147496
DOI: 10.1101/2024.10.10.617696

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