Article

Obesity associated with attenuated tissue immune cell responses in COVID-19

2022-01-18

Abstract excerpt

Obesity is common and associated with more severe COVID-19, proposed to be in part related to an adipokine-driven pro-inflammatory state. Here we analysed single cell transcriptomes from bronchiolar lavage in three adult cohorts, comparing obese (Ob, body mass index (BMI) >30m 2 ) and non-obese (N-Ob, BMI <30m 2 ). Surprisingly, we found that Ob subjects had attenuated lung immune/inflammatory responses in SARS-...

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Literature Corpus work: 047d66e7-ef9c-52e4-911f-77d20b0490cd
DOI: 10.1101/2022.01.14.475727

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