Article

PCSK9 promotes osteogenic differentiation via ERK pathway and has no effect on osteoclast differentiation

2022-08-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Previous studies have demonstrated that PCSK9 was constitutively expressed in osteoclast precursors and played an important role in bone metabolism in periodontitis disease. But the function of PCSK9 in the osteogenesis of hBMSCs and specific mechanism still remains unknown. In this study, we aim to explore the function and mechanism of PCSK9 on regulating osteo...

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Literature Corpus work: 0eeb4664-f0c3-588e-9d04-9a1e28cb8110
DOI: 10.21203/rs.3.rs-1890075/v1

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