Article

Osteoking Promotes Bone Formation and Bone Defect Repair through ZBP1-STAT1-PKR-MLKL-mediated Necroptosis

2023-11-30

Abstract excerpt

<h4>Background: </h4> Osteoking has been used for fracture therapy with a satisfying clinical efficacy. However, its therapeutic properties and the underlying mechanisms remain elusive. <h4>Method: </h4> A bone defect rat model was established to evaluate the pharmacological effects of Osteoking by the dynamic observation of X-ray, micro-CT and histopathologic examination. Transcriptome profiling was performed to...

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Literature Corpus work: 2352a678-0238-5d63-a249-fc515eed428e
DOI: 10.21203/rs.3.rs-3613336/v1

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