Article

Looking for Tumor Specific Transcription Factors. Study of Promoters in Silico

2021-11-12

Abstract excerpt

This study supplements earlier received experimental data using modern databases. Previously tumor-specific activity of several human native and chimeric promoters was demonstrated. Here we compared tumor-specific promoters with promoters of housekeeping genes by the presence of recognition profiles for transcription factors in DNA sequences of the promoters. A number of transcription factor recognition profiles h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0ed56b9e-7349-51c0-8d59-83dfc089b6ae
DOI: 10.1101/2021.11.11.468214

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Looking for Tumor Specific Transcription Factors. Study of Promoters in SilicoDOI 10.1101/2021.11.11.468214Read

Cancer specificity of promoters of the genes controlling cell proliferation.Semantic proximity Read

Epigenetic characterization of housekeeping core promoters and their importance in tumor suppressionSemantic proximity Read

Transcription factors as targets for cancer therapy.Semantic proximity Read

Identification of cancer-related genes and motifs in the human gene regulatory network.Semantic proximity Read

Characteristics of functional enrichment and gene expression level of human putative transcriptional target genesSemantic proximity Read

Cluster analysis and promoter modelling as bioinformatics tools for the identification of target genes from expression array data.Semantic proximity Read

Human PON promoters: from similarity to prediction of polymorphic positions within transcription factor elements.Semantic proximity Read

Comparative analysis of distinct non-coding characteristics potentially contributing to the divergence of human tissue-specific genes.Semantic proximity Read

Management of gene promoter mutations in molecular diagnostics.Semantic proximity Read

Diverse DNA methylation statuses at alternative promoters of human genes in various tissues.Semantic proximity Read

A comparative analysis of the 'other roles' of transcriptional factors from pathogenic organisms.Semantic proximity Read

In vitro and in vivo comparative study of chimeric liver-specific promotersSemantic proximity Read