Article
Cancer specificity of promoters of the genes controlling cell proliferation.
Journal of cellular biochemistry - 1 Feb 2015
Kashkin Kirill, Chernov Igor, Stukacheva Elena, Monastyrskaya Galina, Uspenskaya Natalya, Kopantzev Eugene, Sverdlov Eugene
Abstract excerpt
Violation of proliferation control is a common feature of cancer cells. We put forward the hypothesis that promoters of genes involved in the control of cell proliferation should possess intrinsic cancer specific activity. We cloned promoter regions of CDC6, POLD1, CKS1B, MCM2, and PLK1 genes int...
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