Article

The role of the globular heads of the C1q receptor in TcdA-induced human colonic epithelial cell apoptosis via a mitochondria-dependent pathway

2020-03-11

Abstract excerpt

<h4>Background: </h4> Clostridioides (formerly Clostridium) difficile infection is the leading cause of antibiotic-associated colitis. Studies have demonstrated that C. difficile toxin A (TcdA) can cause apoptosis in many human cell types. The purpose of this study was to investigate the relationships among exposure to TcdA, the role of globular heads receptor of C1q (gC1qR) gene and the underlying intracellular a...

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Literature Corpus work: 0eb48806-2718-57a7-a164-e2dc160c7eb7
DOI: 10.21203/rs.3.rs-16745/v1

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