Article

Inference of annealed protein fitness landscapes with AnnealDCA

2023-05-22

Abstract excerpt

The design of proteins with specific tasks is a major challenge in molecular biology with important diagnostic and therapeutic applications. High-throughput screening methods have been developed to systematically evaluate protein activity, but only a small fraction of possible protein variants can be tested using these techniques. Computational models that explore the sequence space in-silico to identify the fitt...

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Literature Corpus work: 0e496e5b-2918-571e-b140-5e1e2ff05482
DOI: 10.1101/2023.05.19.541442

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