Article

3-hydroxyanthranilic acid – a new metabolite for healthy lifespan extension

2021-06-01

Abstract excerpt

<h4>Summary</h4> The metabolism of tryptophan to nicotinamide adenine dinucleotide (NAD + ) through the kynurenine pathway is increasingly linked to aging and age-associated disease. Kynurenine pathway enzymes and metabolites influence a range of molecular processes critical to healthy aging, including regulation of inflammatory and immune responses, cellular redox homeostasis, and energy production. Aberrant ky...

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Literature Corpus work: 0e19065e-0009-5043-a0c2-1108d8f480f1
DOI: 10.1101/2021.06.01.446651

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