Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3'UTR Variation in Chikungunya Virus.

Journal of virology - 23 Nov 2020

Madden Emily A, Plante Kenneth S, Morrison Clayton R, Kutchko Katrina M, Sanders Wes, Long Kristin M, Taft-Benz Sharon, Cruz Cisneros Marta C, White Ashlyn Morgan, Sarkar Sanjay, Reynolds Grace, Vincent Heather A, Laederach Alain, Moorman Nathanial J, Heise Mark T

Abstract excerpt

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus associated with debilitating arthralgia in humans. RNA secondary structure in the viral genome plays an important role in the lifecycle of alphaviruses; however, the specific role of RNA structure in regulating CHIKV replication is poorly understood. Our previous studies found little conservation in RNA secondary structure between alphaviruses, and this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Chikungunya Fever

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chikungunya virus

Share to Chlorocebus aethiops

Share to Culicidae

Share to Cytopathogenic Effect, Viral

Share to Sequence Analysis

Share to Vero Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 32999019
DOI: 10.1128/JVI.00701-20
PMCID: PMC7925192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3'UTR Variation in Chikungunya Virus.PMID 32999019Read ↗

Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genomes ProductionSemantic proximity Read ↗

Multiple roles of the non-structural protein 3 (nsP3) alphavirus unique domain (AUD) during Chikungunya virus genome replication and transcriptionSemantic proximity Read ↗

A conserved Y-shaped RNA structure in the 3’UTR of chikungunya virus genome as a host-specialized element that modulates viral replication and evolutionSemantic proximity Read ↗

Structural and phenotypic analysis of Chikungunya virus RNA replication elementsSemantic proximity Read ↗

Dynamic molecular epidemiology reveals lineage-associated single-nucleotide variants that alter RNA structure in Chikungunya virusSemantic proximity Read ↗

Dynamic Molecular Epidemiology Reveals Lineage-Associated Single-Nucleotide Variants That Alter RNA Structure in Chikungunya Virus.Semantic proximity Read ↗

Updated Phylogeny of Chikungunya Virus Suggests Lineage-Specific RNA ArchitectureSemantic proximity Read ↗

Identification and Characterization of Novel Chikungunya Virus Polymerase InhibitorsSemantic proximity Read ↗

Genome-wide discovery of local RNA structural elements in Zika virusSemantic proximity Read ↗

Structural divergence creates new functional features in alphavirus genomesSemantic proximity Read ↗

Structure mapping of dengue and Zika viruses reveals new functional long-range interactionsSemantic proximity Read ↗

Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.