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Article

A single rare σ70 variant establishes a unique gene expression pattern in the E. coli pathobiont LF82.

Nucleic acids research - 28 Oct 2024

Arroyo-Mendoza Melissa, Proctor Alexandra, Correa-Medina Abraham, DeWolf Sarah, Brand Meghan Wymore, Rosas Virginia, Lorenzi Hernan, Wannemuehler Michael J, Phillips Gregory J, Hinton Deborah M

Abstract excerpt

LF82, an adherent-invasive Escherichia coli (AIEC) pathobiont, is associated with Crohn's disease, an inflammatory bowel disease of unknown etiology. Although AIEC phenotypes differ from those of 'commensal' or pathogenic E. coli, work has failed to identify genetic features accounting for these differences. We have investigated a natural, but rare, single nucleotide polymorphism (SNP) in LF82 present within the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39258538
DOI: 10.1093/nar/gkae773
PMCID: PMC11514462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A single rare σ70 variant establishes a unique gene expression pattern in the E. coli pathobiont LF82.PMID 39258538Read ↗

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