Article

Genomic diversity of SARS-CoV-2 can be accelerated by mutations in the nsp14 gene

2020-12-26

Abstract excerpt

<h4>ABSTRACT</h4> Coronaviruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), encode a proofreading exonuclease, nonstructural protein 14 (nsp14), that helps ensure replication competence at a low evolutionary rate compared with other RNA viruses. In the current pandemic, SARS-CoV-2 has accumulated diverse genomic mutations including in nsp14. Here, to clarify whether amino acid substit...

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Literature Corpus work: 0db35faa-859c-59f2-8861-0edb8835b7bd
DOI: 10.1101/2020.12.23.424231

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