Article

Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

2020-04-06

Abstract excerpt

<title>Abstract</title> <p>Background. SARS-CoV-2 is a RNA coronavirus responsible for the pandemic of the Severe Acute Respiratory Syndrome (COVID-19). RNA viruses are characterized by a high mutation rate, up to a million times higher than that of their hosts. Virus mutagenic capability depends upon several factors, including the fidelity of viral enzymes that replicate nucleic acids, as SARS-CoV-2 RNA dependen...

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Literature Corpus work: 5c0d3ac2-ab04-5130-97a7-7e034228e8b6
DOI: 10.21203/rs.3.rs-20304/v1

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