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Emerging Mutations in Nsp1 of SARS-CoV-2 and Their Effect on the Structural Stability

6 Oct 2021

Abstract excerpt

The genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes 16 non-structural (Nsp) and 4 structural proteins. Among the Nsps, Nsp1 inhibits host gene expression and also evades the immune system. This protein has been proposed as a target for vaccine development and also for drug design. Owing to its important role, the current study aimed to identify mutations in Nsp1 and their effect on...

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PMID: 34684233
DOI: 10.3390/pathogens10101285

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