Article

Increased Synapse Elimination by Inflammatory Cells Contributes to Long-lasting Post-Stroke Memory Dysfunction in Old Mice

2025-06-15

Abstract excerpt

Old patients are more likely to experience memory dysfunction than young patients after a stroke. It has been reported that brain astrocytes and microglia cause excessive removal of synapses at the acute and subacute stages of stroke, and inhibition of their phagocytosis improved neurobehavioral outcomes. We hypothesized that memory dysfunction in old subjects is associated with increased synapse removal by inflam...

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Literature Corpus work: 0d4a2aeb-6511-580e-abfa-070fa9c81d5b
DOI: 10.1101/2025.06.13.659591

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Increased Synapse Elimination by Inflammatory Cells Contributes to Long-lasting Post-Stroke Memory Dysfunction in Old MiceDOI 10.1101/2025.06.13.659591Read

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