Article

Cell intrinsic signaling in <i>MEN1</i> mutant pancreatic neuroendocrine tumors unveils novel signaling pathways associated with de-differentiation

2020-09-30

Abstract excerpt

<h4>Objectives</h4> Preliminary genomic analysis of primary pancreatic neuroendocrine tumors revealed a complex mutational landscape with four common oncogenic events; however, critical activation pathways responsible for pancreatic neuroendocrine tumor progression and metastasis have yet to be elucidated. Here, we analyzed six primary pancreatic neuroendocrine tumors to determine which pathways are deregulated a...

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Literature Corpus work: 0d3e84f0-4096-5c85-8073-2f645f9beb47
DOI: 10.1101/2020.09.29.318873

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