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Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation

22 Jan 2024

Abstract excerpt

Pancreatic neuroendocrine tumors (PNETs) are characterized by dysregulated signaling pathways that are crucial for tumor formation and progression. The efficacy of traditional therapies is limited, particularly in the treatment of PNETs at an advanced stage. Epigenetic alterations profoundly impact the activity of signaling pathways in cancer development, offering potential opportunities for drug development....

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PMID: 38279330
DOI: 10.3390/ijms25021331

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