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Efficient in vivo genome editing mediated by stem cells-derived extracellular vesicles carrying designer nucleases

2021-02-26

Abstract excerpt

Precise genome editing using designer nucleases (DNs), such as zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and the clustered regularly interspaced short palindromic repeat/Cas9 (CRISPR/Cas9) system, has become a method of choice in a variety of biological and biomedical applications in recent years. Notably, efficacy of these systems is currently under scrutiny in about 5...

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Literature Corpus work
0cf9e9a6-b6fc-55b2-9cc2-5be2dabaf5b9
DOI
10.1101/2021.02.25.432823
Open publication

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Efficient in vivo genome editing mediated by stem cells-derived extracellular vesicles carrying designer nucleasesDOI 10.1101/2021.02.25.432823
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