Article

Osteopontin in colitis-associated carcinoma

2023-12-16

Abstract excerpt

Patients with ulcerative colitis (UC) and Crohn’s disease (CD) face a lifelong risk of developing colitis-associated carcinoma (CAC). Current insights into CAC development originate from murine CAC models, while human CAC studies primarily focus on mutational analysis of patient samples. Although the mutational landscape reveals distinct patterns and frequencies compared to colorectal cancer, it falls short in elu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0cf65a25-335e-5bdc-8240-d1733a69546e
DOI: 10.1101/2023.12.15.571952

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Osteopontin in colitis-associated carcinomaDOI 10.1101/2023.12.15.571952Read

Osteopontin regulates multiple functions contributing to human colon cancer development and progressionSemantic proximity Read

Investigating the Role of SPP1 (Osteopontin) in the Progression of Breast and other CancersSemantic proximity Read

Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironmentSemantic proximity Read

The Significance of Secreted Phosphoprotein 1 in Multiple Human CancersSemantic proximity Read

Colitis-associated neoplasia: molecular basis and clinical translationSemantic proximity Read

The molecular landscape of colitis-associated carcinogenesisSemantic proximity Read

Expression analysis of colon adenocarcinoma in the South Indian population reveals novel signals of pathogenesisSemantic proximity Read

Decoding SPP1 regulation: Genetic and nongenetic insights into its role in disease progressionSemantic proximity Read

Distinct and cooperative roles of host and tumor Osteopontin in colorectal cancer liver metastasisSemantic proximity Read

Expression of osteopontin, a target gene of de-regulated Wnt signaling, predicts survival in colon cancer.Semantic proximity Read

Role of osteopontin in the pathophysiology of cancerSemantic proximity Read

An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasionSemantic proximity Read