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Article

Nuclear entry and CRM1-dependent nuclear export of the Rous sarcoma virus Gag polyprotein.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Scheifele Lisa Z, Garbitt Rachel A, Rhoads Jonathan D, Parent Leslie J

Abstract excerpt

The retroviral Gag polyprotein directs budding from the plasma membrane of infected cells. Until now, it was believed that Gag proteins of type C retroviruses, including the prototypic oncoretrovirus Rous sarcoma virus, were synthesized on cytosolic ribosomes and targeted directly to the plasma membrane. Here we reveal a previously unknown step in the subcellular trafficking of the Gag protein, that of transient...

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Identifiers

PMID: 11891341
DOI: 10.1073/pnas.062652199
PMCID: PMC122628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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