Article

Architecture and evolutionary conservation of <i>Xenopus tropicalis</i> osteoblast-specific regulatory regions shed light on bone diseases and early skeletal evolution

2023-09-01

Abstract excerpt

Understanding the genetic mechanisms underpinning the differentiation of osteoblasts, the bone producing cells, has far reaching implications for skeletal diseases and evolution. To this end, it is crucial to characterize osteoblastic regulatory landscape in a diverse array of distantly-related vertebrate species. By comparing of the ATAC-seq profile of Xenopus tropicalis ( Xt ) osteoblasts to liver, heart and l...

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Literature Corpus work: 0c1d82f9-053f-5e07-a905-4f9bac3a00e4
DOI: 10.1101/2023.08.30.555543

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