Article

Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: A functional and structural impact

2022-12-05

Abstract excerpt

<h4>Background: </h4> Cytochrome P450 4F2 (CYP4F2) enzyme is one of the CYP4 family responsible for the metabolism of fatty acids, therapeutic drugs, and signaling molecules, such as arachidonic acid, tocopherols, and vitamin K. Several reports have demonstrated that missense variant CYP4F2*3 (V433M) cause decreased activity of CYP4F2 and inter-individual variations in warfarin dose in different ethnic groups. How...

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Literature Corpus work: 0c173531-e23d-5959-b5b4-cedf1bf7c949
DOI: 10.21203/rs.3.rs-2154240/v1

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