Article

The Genetic Determinants of Aortic Distension

2021-10-25

Abstract excerpt

As the largest conduit vessel, the aorta is responsible for the conversion of phasic systolic inflow from ventricular ejection into more continuous blood delivery to peripheral arteries. Distension during systole and recoil during diastole conserves ventricular energy and is enabled by the specialized composition of the aortic extracellular matrix. Aortic distensibility decreases with age and prematurely in vascul...

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Literature Corpus work: 0c07f7a0-b2b0-5034-919d-72f5881f74fe
DOI: 10.1101/2021.10.16.21265089

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