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Article

Genomic insights in ascending aortic size and distensibility

28 Dec 2021

Abstract excerpt

BACKGROUND: Alterations in the anatomic and biomechanical properties of the ascending aorta (AAo) can give rise to various vascular pathologies. The aim of the current study is to gain additional insights in the biology of the AAo size and function. METHODS: We developed an AI based analysis pipeline for the segmentation of the AAo, and the extraction of AAO parameters. We then performed genome-wide association...

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PMID: 34968759
DOI: 10.1016/j.ebiom.2021.103783

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