Article

Combination low dose sulphonylurea and DPP4 inhibitor have potent glucose lowering effect through augmentation of beta cell function without increase in hypoglycaemia: a randomised crossover study

2023-08-24

Abstract excerpt

<h4>Aims/Hypothesis</h4> It is important to address our use of cheaper generic therapies as the global prevalence of type 2 diabetes (T2DM) will surpass 600 million by 2035. Negative aspects of SU may be avoided by their use at low dose. We have previously shown that 20mg standard release gliclazide reduces plasma glucose through augmentation of the classical incretin effect, increased beta-cell glucose sensitivit...

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Literature Corpus work: 0bd0530d-adb1-5e62-a817-4c2c0a113318
DOI: 10.1101/2023.08.22.23294403

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Combination low dose sulphonylurea and DPP4 inhibitor have potent glucose lowering effect through augmentation of beta cell function without increase in hypoglycaemia: a randomised crossover studyDOI 10.1101/2023.08.22.23294403Read

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