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Tirzepatide as Monotherapy Improved Markers of Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes (SURPASS-1)

6 Mar 2023

Abstract excerpt

Abstract Context Tirzepatide is a glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist approved for treatment of type 2 diabetes (T2D). SURPASS-1, a phase 3 trial of tirzepatide monotherapy in people with early T2D, enables evaluating effects of tirzepatide on pancreatic beta-cell function and insulin sensitivity (IS) without other background antihyperglycemic medications....

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PMID: 37153701
DOI: 10.1210/jendso/bvad056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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