Article
Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions
2020-05-02
Abstract excerpt
Fibrotic scar tissue limits central nervous system regeneration in adult mammals. The extent of fibrotic tissue generation and distribution of stromal cells across different lesions in the brain and spinal cord has not been systematically investigated in mice and humans. Furthermore, it is unknown whether scar-forming stromal cells have the same origin throughout the central nervous system and in different types o...
Topics
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- Barrier Structure and Function Studies
- Cancer Cells and Metastasis
- Fibroblast Growth Factor Research
- Lymphatic System and Diseases
- Mesenchymal stem cell research
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
Identifiers and source
- Literature Corpus work
- 0bc7fd2c-0781-5a46-9eb4-c85de80362ab
- DOI
- 10.1101/2020.04.30.068965
