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Origins of fibrosis: pericytes take centre stage

30 Aug 2013

Abstract excerpt

Pericytes are ubiquitous perivascular cells that have recently attracted interest as potential myofibroblast precursors. In turn, myofibroblasts are the major source of extracellular matrix components that accumulate during tissue fibrosis. Given the worldwide burden of fibrotic disease and paucity of therapeutic options available to halt its progression, elucidating the origins of myofibroblasts is of prime...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 24049641
DOI: 10.12703/p5-37

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