Article

Effect of epigenetic activating of Dlk1-Dio3 imprinted cluster on miR-370 expression due to folate deficiency during nerve development

2022-03-29

Abstract excerpt

<title>Abstract</title> <p>Proper Dlk1-Dio3 imprinting plays a critical role in embryogenesis, and folic acid deficiency may affect the imprinting of this locus through epigenetic regulation. However, whether and how folic acid directly impacts the imprinting status of Dlk1-Dio3 to affect neural development remain unclear. Here, we found decreased IG-DMR methylation in the folate-deficient encephalocele in humans...

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Literature Corpus work: 0b9225d9-778b-5488-bbf9-1ca615f473b7
DOI: 10.21203/rs.3.rs-1464837/v1

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