Article

Impaired Myofibroblast Proliferation is a Central Feature of Pathologic Post-Natal Alveolar Simplification

2023-12-23

Abstract excerpt

Premature infants with bronchopulmonary dysplasia (BPD) have impaired alveolar gas exchange due to alveolar simplification and dysmorphic pulmonary vasculature. Advances in clinical care have improved survival for infants with BPD, but the overall incidence of BPD remains unchanged because we lack specific therapies to prevent this disease. Recent work has suggested a role for increased transforming growth factor-...

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Literature Corpus work: 0b4d9688-6833-5fdd-9fd1-259e2ed19b9e
DOI: 10.1101/2023.12.21.572766

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