Article

Development and characterisation of an optimised <i>in vitro</i> differentiation protocol for deriving hepatocyte-like cells from mouse embryonic stem cells

2026-05-15

Abstract excerpt

<h4>Introduction</h4> Reliable generation of hepatocyte-like cells (HLCs) from pluripotent stem cells remains limited by heterogeneity and incomplete maturation of the cells. Derivation of induced pluripotent- and embryonic stem cells into hepatocytes typically relies on complex, and costly reagent-intensive protocols, with inconsistent reporting of differentiation efficiencies and functional maturation criteria....

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Literature Corpus work: 0b13bca5-4b0d-5263-99c3-94f4fbe79f6d
DOI: 10.64898/2026.05.13.724236

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