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Article

Polyvalent Guide RNAs for CRISPR Antivirals

2021-02-25

Abstract excerpt

<h4>ABSTRACT</h4> CRISPR biotechnologies, where CRISPR effectors recognize and degrade specific nucleic acid targets that are complementary to their guide RNA (gRNA) cofactors, have been primarily used as a tool for precision gene editing 1 but possess an emerging potential for novel antiviral diagnostics, prophylactics, and therapeutics. 2–5 In gene editing applications, significant efforts are made to limit t...

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Literature Corpus work
0b0b4112-a21d-5652-a37c-a5328956d154
DOI
10.1101/2021.02.25.430352
Open publication

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