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A review of virus host factor discovery using CRISPR screening

18 Oct 2024

Abstract excerpt

The emergence of genome-scale forward genetic screening techniques, such as Haploid Genetic screen and clustered regularly interspaced short palindromic repeats (CRISPR) knockout screen has opened new horizons in our understanding of virus infection biology. CRISPR screening has become a popular tool for the discovery of novel host factors for several viruses due to its specificity and efficiency in genome...

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PMID: 39422472
DOI: 10.1128/mbio.03205-23

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