Article

Cas13a-based multiplex RNA targeting for potato virus Y

2023-03-07

Abstract excerpt

<title>Abstract</title><p>CRISPR-Cas systems endow the bacterial and archaeal species with adaptive immunity mechanisms to fend off invading phages and foreign plasmids. The class 2 type VI CRISPR/Cas effector Cas13a has been harnessed to confer the protection against RNA viruses in diverse eukaryotic species. However, whether gRNA targeting sites have effects on the efficiency of RNA viruses inhibition is unknown...

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Literature Corpus work: d8df1349-58fb-5742-9b40-062e8c5130cd
DOI: 10.21203/rs.3.rs-2555061/v1

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