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Epithelial–mesenchymal plasticity in cancer: signaling pathways and therapeutic targets

1 Aug 2024

Abstract excerpt

Currently, cancer is still a leading cause of human death globally. Tumor deterioration comprises multiple events including metastasis, therapeutic resistance and immune evasion, all of which are tightly related to the phenotypic plasticity especially epithelial-mesenchymal plasticity (EMP). Tumor cells with EMP are manifest in three states as epithelial-mesenchymal transition (EMT), partial EMT, and...

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PMID: 39092293
DOI: 10.1002/mco2.659

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