Article
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation.
Trends in molecular medicine - 1 Mar 2024
Hausmann Annika, Steenholdt Casper, Nielsen Ole H, Jensen Kim B
Abstract excerpt
The intestinal epithelium fulfills important physiological functions and forms a physical barrier to the intestinal lumen. Barrier function is regulated by several pathways, and its impairment contributes to the pathogenesis of inflammatory bowel disease (IBD), a chronic inflammatory condition affecting more than seven million people worldwide. Current treatment options specifically target inflammatory mediators...
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