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Article

Role of Rho GTPases in inflammatory bowel disease

23 Jan 2023

Abstract excerpt

Rat sarcoma virus homolog (Rho) guanosine triphosphatases (GTPases) function as "molecular switch" in cellular signaling regulation processes and are associated with the pathogenesis of inflammatory bowel disease (IBD). This chronic intestinal tract inflammation primarily encompasses two diseases: Crohn's disease and ulcerative colitis. The pathogenesis of IBD is complex and considered to include four main...

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PMID: 36690621
DOI: 10.1038/s41420-023-01329-w

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