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Article

Immunopathogenesis of Crohn's disease.

JPEN. Journal of parenteral and enteral nutrition - 1 Jan 2000

MacDonald Thomas T, Di Sabatino Antonio, DiSabatino Antonio, Gordon John N

Abstract excerpt

This review highlights the huge advances made in the understanding of Crohn's disease in the last 15 years. The pathogenic immune response in the gut wall is a highly polarised T helper cell type 1 response, probably directed against antigens of the commensal flora. There is marked over-expressio...

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Source

Identifiers

PMID: 15980273
DOI: 10.1177/01486071050290S4S118

Genes

DLG5
TFG
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15980273-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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