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Papillomavirus Infectious Pathways: A Comparison of Systems

4 Aug 2015

Abstract excerpt

The HPV viral lifecycle is tightly linked to the host cell differentiation, causing difficulty in growing virions in culture. A system that bypasses the need for differentiating epithelium has allowed for generation of recombinant particles, such as virus-like particles (VLPs), pseudovirions (PsV), and quasivirions (QV). Much of the research looking at the HPV life cycle, infectivity, and structure has been...

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PMID: 26247955
DOI: 10.3390/v7082823

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